Death Effector Domain Containing 2 (DEDD2) (Middle Region) Peptide
DEDD2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975717
Quick Overview for Death Effector Domain Containing 2 (DEDD2) (Middle Region) Peptide (ABIN975717)
Target
DEDD2
(Death Effector Domain Containing 2 (DEDD2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PQQQSEPARP SSEGKVTCDI RLRVRAEYCE HGPALEQGVA SRRPQALARQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DEDD2 Antibody(ARP52558_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DEDD2 (Death Effector Domain Containing 2 (DEDD2))
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Background
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DEDD2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. DEDD2 may regulate degradation of intermediate filaments during apoptosis. DEDD2 may play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Alias Symbols: FLAME-3
Protein Interaction Partner: CASP10,CASP8,CFLAR,DEDD,DEDD2,GTF3C3,CASP10,CASP8,CFLAR,DEDD,DEDD2,GTF3C3
Protein Size: 326 -
Molecular Weight
- 36 kDa
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Gene ID
- 162989
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NCBI Accession
- NM_133328, NP_579874
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UniProt
- Q8WXF8
Target
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